EPILEPSY UPDATE

8 February 2019

Epilepsy and Family


9 February 2019

Epilepsy therapies


PADOVA - BOTANICAL GARDEN


Over 65 million people worldwide suffer from epilepsy, which is an important cause of disability, morbidity, mortality, social stigma and high costs. To date, epilepsy is intractable in about a third of the patients, and only a minority of drug-resistant patients benefit from epilepsy surgery.

In the last ten years, though, progress has been made in understanding the physiopathological mechanisms of this condition, harboring the potential for improved diagnostic and therapeutic strategies, and therefore a better quality of life for epileptic patients.


Thanks to the investigative contribution of optogenetics, evidence is being put forward for a direct role of astrocytes in the generation of epileptic seizures, making these cells new potential therapeutic targets. On the other hand, the identification of inflammatory and immunological mechanisms involved in different phases of epileptogenesis possibly supports the use of neuroimmunomodulatory agents, at least in some settings or disease stages.

Moreover, the identification of new therapeutic strategies, as much as the consolidation and implementation of more traditional approaches like epilepsy surgery, undoubtedly benefit from the surprising advance of diagnostic techniques, especially in the fields of genetics, epigenetics, integrated and multimodal imaging and structural and functional imaging. The challenge lies in the timely and effective translation of the recent advances in basic epilepsy research to the clinical setting also through an open and ongoing communication and sharing between researchers and clinicians. This represents the main aim of this workshop.

8th february 2019

9th february 2019

Moderators:
Giada Pauletto
Maurizio Corbetta

11.40
Imaging, presurgical work-up and surgery in adults
Francesco Cardinale
Laura Tassi

12.10
Imaging, presurgical work-up and surgery in children
Helen Cross
Martin Tisdall

13.10
Discussion

13.30
Italian Light Lunch


14.30
“Le tre del mattino”
Gianrico Carofiglio, writer

Moderators:
Francesco Brigo
Paolo Manganotti

15.00
Pregnancy and Epilepsy
Torbjorn Tomson

15.30
Ketogenic Diet
Anna Tagliabue
Alberto Burlina

16.00
What about
a seizure-alert device
Matteo Lai

16.30
Farewell
Federica Ranzato
Stefano Bellon    

17.00
Evaluation questionnaire

Scientific office: Stefano Bellon - Clementina Boniver - Maurizio Corbetta - Bruno Giometto - Stefano Sartori - Marilena Vecchi


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